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アイテム
ヒラメのエドワジュラ症に対するワクチンの効果
http://hdl.handle.net/10126/4371
http://hdl.handle.net/10126/43716938d6ec-df28-4ec8-9b54-1d9eef328101
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2010-03-17 | |||||
タイトル | ||||||
タイトル | ヒラメのエドワジュラ症に対するワクチンの効果 | |||||
言語 | ja | |||||
タイトル | ||||||
タイトル | Efficacy of vaccine against edwardsiellosis of the Japanese flounder, Paralichthys olivaceus | |||||
言語 | en | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
言語 | en | |||||
主題 | Edwardsiella tarda | |||||
キーワード | ||||||
言語 | en | |||||
主題 | Japanese flounder | |||||
キーワード | ||||||
言語 | en | |||||
主題 | vaccine | |||||
キーワード | ||||||
言語 | en | |||||
主題 | immunization | |||||
キーワード | ||||||
言語 | en | |||||
主題 | serotype | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
川合, 研児
× 川合, 研児× 青山, 雅人 |
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著者別名 | ||||||
姓名 | Kawai, Kenji | |||||
著者別名 | ||||||
姓名 | Aoyama, Masato | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Efficacy of the vaccine against Edwardsiella tarda infection in Japanese flounder Paralichthys olivaceus was studied by comparing the immunizing bacterial strains of different origins and three administration methods of the vaccine. Two groups of flounder, the mean body weight was about 53 g, were immunized intraperitoneally (IP) with formalin killed cells (FKCs) of E. tarda HH-1 strain and EF-1 strain. The serotypes of the two strain were preliminary clarified identical. Strain HH-1 was originally isolated from a flounder, and strain EF-1 was isolated from an eel. The immunized fish and unimmunized control fish were challenged by IP injection with strain HH-1. Comparison of different administration methods was executed using fish groups (about 53 g) immunized by IP injection, oral administration and immersion with FKC of strain HH-1 and challenged by IP injection with live cells of strain HH-1. Immune response (antibody titer in the serum and phagocytic activity) was also compared between groups of different immunization methods. Additionally, the effect of encapsulation of oral administration vaccine to examine anti-acid resistance of the vaccine in the stomach was examined by immunizing fish of 86 g with FKC of strain HH-1 then challenging with live cells of the same strain. The result in the mortality in the fish immunized with strains HH-1 and EF-1 was not significantly different at 5% level, which indicates origins of the strains does not affect efficacy of the vaccine as far as the serotype is sarne. Both survival rate and immune response were the highest in the group of IP injection followed by oral administration and immersion. Encapsulation of the vaccine in oral administration did not show advantageous effect than the uncapsulated vaccine. It may be attributed that the capsule did not release the vaccine antigen in the gastro-intestinal tract effectively. | |||||
書誌情報 |
Bulletin of marine sciences and fisheries, Kochi University 巻 20, p. 35-43, 発行日 2001-03-15 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 03879763 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10778872 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版者 | ||||||
出版者 | 高知大学海洋生物教育研究センター | |||||
言語 | ja |