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Expression of fascin-1, an actin-bundling protein, in migrating hepatoblasts during rat liver development
http://hdl.handle.net/10126/498
http://hdl.handle.net/10126/4983f072c27-6754-48dd-892b-13c9f994cd2a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
hayashi_Expression.pdf (847.8 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2008-11-14 | |||||
| タイトル | ||||||
| タイトル | Expression of fascin-1, an actin-bundling protein, in migrating hepatoblasts during rat liver development | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | fascin | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | hepatoblast | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | immunohistochemistry | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | migration | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | ultrastructure | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Hayashi, Yoshihiro
× Hayashi, Yoshihiro× Toda, Katsumi× Saibara, Toshiji× Okamoto, Sumika× Osanai, Makoto× Enzan, Hideaki× Lee, Gang-Hong |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Fascin-1 is an actin-bundling protein localized at the core actin bundles within microvillar projections and filopodial extensions in migrating cells. It is expressed at a low level in normal epithelial cells, but at a high level in tumor cells, indicating its importance in the invasion and progression of tumor cells. In addition, fascin-1 is expressed in human and murine embryos, especially at high levels in developing nervous tissues. In this study, we immunohistochemically investigated the expression patterns of fascin-1 during the early stages of rat hepatogenesis. A high expression of fascin-1 was detected in the liver bud and hepatoblasts at embryonic day (ED) 10.5, 11.5 and 12.5. The expression fell by ED13.5 and was not detectable at ED14.5. These observations demonstrated that the expression of fascin-1 is correlated with the migration activity of hepatoblasts during the early stages of liver development in rats. | |||||
| 書誌情報 |
en : Cell and tissue research 巻 334, 号 2, p. 219-226, 発行日 2008-10-15 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0302766X | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00600105 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1007/s00441-008-0683-8 | |||||
| 権利 | ||||||
| 権利情報 | The original publication is available at www.springerlink.com | |||||
| 情報源 | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.springerlink.com/content/r23363757t54u184/ | |||||
| 関連名称 | http://www.springerlink.com/content/r23363757t54u184/ | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 出版者 | ||||||
| 出版者 | Springer | |||||
