{"created":"2023-05-15T15:31:34.353302+00:00","id":1390,"links":{},"metadata":{"_buckets":{"deposit":"42cf740b-11aa-4047-a2a8-30cf61c0d327"},"_deposit":{"created_by":3,"id":"1390","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"1390"},"status":"published"},"_oai":{"id":"oai:kochi.repo.nii.ac.jp:00001390","sets":["80:82"]},"author_link":["7828","7826","7832","7831","7829","7827","7830"],"item_11_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-10-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"226","bibliographicPageStart":"219","bibliographicVolumeNumber":"334","bibliographic_titles":[{},{"bibliographic_title":"Cell and tissue research","bibliographic_titleLang":"en"}]}]},"item_11_description_14":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_11_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Fascin-1 is an actin-bundling protein localized at the core actin bundles within microvillar projections and filopodial extensions in migrating cells. It is expressed at a low level in normal epithelial cells, but at a high level in tumor cells, indicating its importance in the invasion and progression of tumor cells. In addition, fascin-1 is expressed in human and murine embryos, especially at high levels in developing nervous tissues. In this study, we immunohistochemically investigated the expression patterns of fascin-1 during the early stages of rat hepatogenesis. A high expression of fascin-1 was detected in the liver bud and hepatoblasts at embryonic day (ED) 10.5, 11.5 and 12.5. The expression fell by ED13.5 and was not detectable at ED14.5. These observations demonstrated that the expression of fascin-1 is correlated with the migration activity of hepatoblasts during the early stages of liver development in rats.","subitem_description_type":"Abstract"}]},"item_11_publisher_31":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer"}]},"item_11_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1007/s00441-008-0683-8","subitem_relation_type_select":"DOI"}}]},"item_11_relation_13":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://www.springerlink.com/content/r23363757t54u184/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.springerlink.com/content/r23363757t54u184/","subitem_relation_type_select":"URI"}}]},"item_11_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"The original publication is available at www.springerlink.com"}]},"item_11_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0302766X","subitem_source_identifier_type":"ISSN"}]},"item_11_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00600105","subitem_source_identifier_type":"NCID"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hayashi, Yoshihiro"}],"nameIdentifiers":[{"nameIdentifier":"7826"}]},{"creatorNames":[{"creatorName":"Toda, Katsumi"}],"nameIdentifiers":[{"nameIdentifier":"7827"}]},{"creatorNames":[{"creatorName":"Saibara, Toshiji"}],"nameIdentifiers":[{"nameIdentifier":"7828"}]},{"creatorNames":[{"creatorName":"Okamoto, Sumika"}],"nameIdentifiers":[{"nameIdentifier":"7829"}]},{"creatorNames":[{"creatorName":"Osanai, Makoto"}],"nameIdentifiers":[{"nameIdentifier":"7830"}]},{"creatorNames":[{"creatorName":"Enzan, Hideaki"}],"nameIdentifiers":[{"nameIdentifier":"7831"}]},{"creatorNames":[{"creatorName":"Lee, Gang-Hong"}],"nameIdentifiers":[{"nameIdentifier":"7832"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-04-20"}],"displaytype":"detail","filename":"hayashi_Expression.pdf","filesize":[{"value":"847.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"hayashi_Expression.pdf","url":"https://kochi.repo.nii.ac.jp/record/1390/files/hayashi_Expression.pdf"},"version_id":"469d007b-4527-46c4-ad6c-ee751b6fdb1d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"fascin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hepatoblast","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"immunohistochemistry","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"migration","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ultrastructure","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Expression of fascin-1, an actin-bundling protein, in migrating hepatoblasts during rat liver development","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Expression of fascin-1, an actin-bundling protein, in migrating hepatoblasts during rat liver development","subitem_title_language":"en"}]},"item_type_id":"11","owner":"3","path":["82"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-11-14"},"publish_date":"2008-11-14","publish_status":"0","recid":"1390","relation_version_is_last":true,"title":["Expression of fascin-1, an actin-bundling protein, in migrating hepatoblasts during rat liver development"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-05-15T18:02:42.030331+00:00"}